T-cell Repertoire as a Biomarker in Advanced NSCLC
Role: PI | MSD Global Translational Research Grant
Aim: Evaluate TCR dynamics to predict response to pembrolizumab-based therapy
https://trial.medpath.com/clinical-trial/e1f90f45b6ce8863/nct06951399-t-cell-pembrolizumab-non-small-cell-lung-cancer
 

TCR Repertoire in Perioperative Immunotherapy for Resectable NSCLC
Role: PI | Sponsor: Roche
Aim: Track T-cell clonal expansion before and after neoadjuvant chemo-IO
 

Detecting MRD in Lung Cancer Using an Epigenetic-Based Liquid Biopsy Approach
Role: PI | Sponsor: JAXBIO
Aim: Assess the utility of a methylation-based liquid biopsy to detect minimal residual disease (MRD), monitor treatment response, and enable early identification of recurrence in NSCLC